Digestive Disease Center

Leading the world in digestive health through innovation and excellence.
M.U.S.C. Digestive Disease Center logoChanging What's Possible®

MUSC Digestive Disease Center

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Reception: 843-792-6999Scheduling: 843-792-6982Clinical Trials: 843-876-4303
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Patient Care

Our physicians and surgeons strive to provide you with the care and information you want.


Reaching out to the professional community, knowing that education is the key to better medicine.


A wide variety of clinical trials and research are the basis of our search for better G.I. solutions.



Gastritis occurs when the lining of the stomach becomes inflamed or swollen. There can be many possible causes for gastritis and can last from short time periods to many years.

Read about other G.I. diseases.

Abdominal Pain


There are two different types of abdominal pain: acute, which is normally sudden and severe; and chronic, which can be described as being less severe, longer lasting and perhaps intermittent.



A colonoscopy allows a physician to see inside your large intestine via your anus using a long, narrow, flexible tube called a colonoscope that contains a tiny light and camera at one end.

Read about other G.I. procedures.

MUSC Anchors Major Publication on Sphincter of Oddi Dysfunction

The sphincter of Oddi controls the flow of bile and pancreatic juices from the liver and pancreas into the duodenum. Dysfunction of the sphincter is often considered as a cause of biliary-type pain in patients who have previously undergone gall bladder removal. Dr. Peter Cotton and colleagues from seven expert centers in the USA undertook a trial in 214 patients in which the standard approach (ERCP with manometry and sphincterotomy) was compared with a sham procedure. Patients did not know what treatment they had received. Read more

Brenda Hoffman, MD, FACP, FACGChief, Endosonography; Leader, G.I. Cancer Program; Professor of Medicine

portrait of Dr. Brenda Hoffman
Dr. Brenda Hoffman

Dr. Brenda Hoffman, whose clinical interests are endoscopic ultrasound, capsule endoscopy, laser therapy and therapeutic endoscopy, received her M.D. degree from the University of Kentucky College of Medicine in 1983 and completed her Gastroenterology Fellowship at the Medical University of South Carolina in 1989.

Dr. Hoffman is board certified in Internal Medicine and Gastroenterology and is a member of several organizations, including the American Gastroenterological Association, the American Society of Gastrointestinal Endoscopy, and the American College of Gastroenterology.View faculty list

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Why should I visit the Medical University of South Carolina?

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MUSC Ashley River Tower

Your doctor will probably agree with you about your preference to come to MUSC. We offer excellent patient care at a state-of-the-art facility, in a historic setting in the southeastern United States. Our doctors are nationally ranked among the highest in the nation. We employ a multidisciplinary approach to the treatment of patients using the latest technology in medicine.

Come see why MUSC is changing what's possible®.

Read more about why you should choose MUSC for your healthcare needs.